Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19531664 | 0.91 | ESR2 (0.52) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL31486447 | 0.89 | ESR2 (0.42) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL20645631 | 0.86 | ESR2 (0.47) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL6421569 | 0.82 | ESR2 (0.55) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL2921637 | 0.81 | ESR2 (0.52) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL13981293 | 0.81 | ESR2 (0.52) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL22369230 | 0.81 | ESR2 (0.54) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL32660197 | 0.81 | ESR2 (0.54) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL14876121 | 0.81 | NR1H2 (0.60) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL1017283 | 0.81 | ESR2 (0.54) | ESR2NR1H2BRD4CREBBPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5698692-A | INHIBIT BINDING BETWEEN PLATELET MEMBRANE GLYCOPROTEIN AND FIBRINOGEN | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |