Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 17/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553538 | 0.87 | TSHR (0.49) | TSHRPPARG | |
| SCHEMBL8550235 | 0.86 | TSHR (0.49) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8554111 | 0.85 | TSHR (0.48) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8553542 | 0.85 | TSHR (0.49) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8557746 | 0.85 | TSHR (0.45) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8605562 | 0.84 | TSHR (0.50) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8555170 | 0.83 | PPARG (0.43) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8554854 | 0.83 | TSHR (0.46) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8554282 | 0.82 | TSHR (0.48) | TSHRXIAPPPARG | |
| SCHEMBL8602742 | 0.82 | TSHR (0.55) | TSHRXIAPPPARGALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |