Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540744 | 0.79 | TACR1 (0.69) | TACR1SLC6A4 | |
| SCHEMBL6494192 | 0.77 | TACR1 (0.59) | TACR1SLC6A4 | |
| SCHEMBL6494539 | 0.77 | TACR1 (0.59) | TACR1SLC6A4 | |
| SCHEMBL6286564 | 0.76 | TACR1 (0.60) | TACR1SLC6A4 | |
| SCHEMBL6483982 | 0.76 | TACR1 (0.67) | TACR1SLC6A4 | |
| SCHEMBL6483987 | 0.76 | TACR1 (0.67) | TACR1SLC6A4 | |
| SCHEMBL6495575 | 0.76 | TACR1 (0.67) | TACR1SLC6A4 | |
| SCHEMBL6482147 | 0.76 | TACR1 (0.67) | TACR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8541648 | 0.76 | TACR1 (0.59) | TACR1SLC6A4 | |
| SCHEMBL14541664 | 0.75 | TACR1 (0.55) | TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760018-A | Gem-disubstituted azacyclic tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 1998-06-02 | — | — | US | claimed |
| US-5760018-A | Gem-disubstituted azacyclic tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 1998-06-02 | — | — | US | disclosed |