Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 14/20 | 0.62 |
| ▸ | NPC1 | O15118 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270133 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL233270 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2629279 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8125122 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4290502 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10253092 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16594526 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6189521 | 0.81 | CDK2 (0.75) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16594522 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16607118 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830349-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996039393-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-12 | — | — | WO | claimed |