Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.48 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557320 | 1.00 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL5007865 | 0.89 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL16994096 | 0.89 | CYSLTR2 (0.52) | CYSLTR1CYSLTR2 | |
| SCHEMBL457834 | 0.88 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL2789885 | 0.88 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL3380397 | 0.88 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL1947901 | 0.88 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL457833 | 0.88 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL16994076 | 0.87 | CYSLTR2 (0.51) | CYSLTR1CYSLTR2 | |
| SCHEMBL3778182 | 0.87 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840728-A1 | HETEROARYL DIOL ACIDS AS LEUKOTRIENE ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996040638-A1 | HETEROARYL DIOL ACIDS AS LEUKOTRIENE ANTAGONISTS | MERCK FROSST CANADA INC. (US) | 1996-12-19 | — | — | WO | disclosed |