Fluroxypyr

Fluroxypyr

SCHEMBL8557509

Nc1c(Cl)c(F)nc(OCC(=O)O)c1Cl.O=C(O)COc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 4/20 0.33
PTGDR2 Q9Y5Y4 4/20 0.33
HIF1A Q16665 1/20 0.33
KMT2A Q03164 1/20 0.33
PLAU P00749 2/20 0.32
MCL1 Q07820 1/20 0.32
PTGDR Q13258 2/20 0.31
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluroxypyr SCHEMBL29396793 0.87 TDP1 (0.35) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL5158164 0.87 TDP1 (0.35) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL23545 0.87 TDP1 (0.35) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL30612286 0.86 TDP1 (0.34) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL21112037 0.86 TDP1 (0.34) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL22163789 0.86 TDP1 (0.34) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL22041988 0.86 TDP1 (0.34) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL28803956 0.83 IAPP (0.34) KDM4EPKMHTTTDP1PTGDR2
Fluroxypyr SCHEMBL28104827 0.83 MAPT (0.33) KDM4EPKMHTTTDP1HIF1A
Triclopyr SCHEMBL37162 0.83 TDP1 (0.45) KDM4EPKMHTTTDP1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106793761-A Herbicide tolerance genes and methods of use thereof 孟山都技术公司 2017-05-31 CN disclosed
EP-0843666-A1 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES DOWELANCO (US) 1998-05-27 EP disclosed
WO-1997037978-A1 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES DOWELANCO (US) 1997-10-16 WO disclosed