Cyclohexanone Oxime

Cyclohexanone Oxime

SCHEMBL8558306

NC(=O)O.ON=C1CCCCC1

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.70
CASP1 P29466 1/20 0.70
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
FAAH O00519 1/20 0.36
ABHD16A O95870 1/20 0.36
PLA2G7 Q13093 1/20 0.36
NCEH1 Q6PIU2 1/20 0.36
DAGLB Q8NCG7 1/20 0.36
DAGLA Q9Y4D2 1/20 0.36
RAB9A P51151 3/20 0.35
GAA P10253 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ACHE P22303 1/20 0.35
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 3/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexanone Oxime SCHEMBL9425289 0.90 TSHR (0.78) TSHRCASP1KMT2AMEN1FAAH
Cyclohexanone Oxime SCHEMBL28084559 0.87 TSHR (0.93) TSHRCASP1KMT2AMEN1RAB9A
Cyclohexanone Oxime SCHEMBL8106638 0.85 TSHR (0.70) TSHRCASP1KMT2AMEN1RAB9A
Cyclohexanone Oxime SCHEMBL27524418 0.84 TSHR (0.88) TSHRCASP1KMT2AMEN1ESR2
Cyclohexanone Oxime SCHEMBL37995 0.84
Cyclohexanone Oxime SCHEMBL11884936 0.84 TSHR (1.00) TSHRCASP1KMT2AMEN1RAB9A
SCHEMBL3472303 0.84 TSHR (1.00) TSHRCASP1KMT2AMEN1RAB9A
SCHEMBL3190316 0.84 TSHR (1.00) TSHRCASP1KMT2AMEN1RAB9A
SCHEMBL3472281 0.84 TSHR (1.00) TSHRCASP1KMT2AMEN1RAB9A
SCHEMBL1025357 0.84 TSHR (1.00) TSHRCASP1KMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP disclosed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US disclosed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed