Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19714 | 0.82 | — | — | |
| Bromide SCHEMBL28102152 | 0.82 | — | — | |
| Bromide SCHEMBL2957398 | 0.67 | — | — | |
| Bromide SCHEMBL4374445 | 0.67 | — | — | |
| Bromide SCHEMBL6578287 | 0.67 | — | — | |
| Water SCHEMBL25327325 | 0.67 | — | — | |
| Bromide SCHEMBL11351766 | 0.67 | — | — | |
| Water SCHEMBL897018 | 0.67 | — | — | |
| Bromide SCHEMBL21995710 | 0.67 | — | — | |
| Bromide SCHEMBL9766448 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694228-B | A method of preparing Pitavastatin Calcium key intermediate | 北京华禧联合科技发展有限公司 | 2018-08-28 | — | — | CN | claimed |
| CN-103664861-B | A kind of new method that Olopatadine hydrochloride is prepared with high activity organic zinc reagent | 北京华禧联合科技发展有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-103694228-A | New method of pitavastatin calcium key intermediate | BEIJING HUAXI LIANHE TECHNOLOGY DEV CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-103664861-A | Novel method for preparing olopatadine hydrochloride by using high-activity organic zinc reagent | BEIJING HUAXI LIANHE TECHNOLOGY DEV CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-103694228-B | A method of preparing Pitavastatin Calcium key intermediate | 北京华禧联合科技发展有限公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-103694228-A | New method of pitavastatin calcium key intermediate | BEIJING HUAXI LIANHE TECHNOLOGY DEV CO LTD | 2014-04-02 | — | — | CN | disclosed |
| US-5783104-A | ALKALI METAL, ALKALINE EARTH METAL, TRANSITION METAL, ZINC SALTS, GERMANIUM COMPOUND; CORROSION RESISTANCE | GAS RESEARCH INSTITUTE (US) | 1998-07-21 | — | — | US | disclosed |
| US-5653117-A | ALSO CONTAINING LITHIUM AND ZINC HALIDES; CORROSION RESISTANCE | GAS RESEARCH INSTITUTE (US) | 1997-08-05 | — | — | US | disclosed |