Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563252 | 0.88 | TP53 (0.47) | ROCK2 | |
| SCHEMBL7331304 | 0.85 | KMT2A (0.48) | KMT2AMEN1AVPR2AVPR1APOLB | |
| SCHEMBL8556932 | 0.83 | AVPR2 (0.48) | KMT2AMEN1AVPR2AVPR1APOLB | |
| SCHEMBL8314597 | 0.79 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL7330829 | 0.79 | AVPR1A (0.63) | AVPR2AVPR1A | |
| SCHEMBL8317444 | 0.77 | AVPR1A (0.48) | KMT2AAVPR2AVPR1A | |
| SCHEMBL8561770 | 0.77 | AVPR2 (0.47) | KMT2AMEN1AVPR2AVPR1A | |
| SCHEMBL7414169 | 0.77 | AVPR2 (0.45) | KMT2AMEN1AVPR2AVPR1A | |
| SCHEMBL8557382 | 0.77 | AVPR2 (0.50) | KMT2AMEN1AVPR2AVPR1APOLB | |
| SCHEMBL8556495 | 0.77 | AVPR2 (0.55) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |