Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910894 | 0.84 | PARP1 (0.47) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL4147944 | 0.81 | DAO (0.55) | MEN1KMT2APARP1KDM4EDAO | |
| SCHEMBL31236110 | 0.77 | PARP1 (0.52) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL29580191 | 0.73 | PSMB8 (0.55) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL22292519 | 0.73 | PARP1 (0.52) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL2639618 | 0.73 | PARP1 (0.52) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL4706735 | 0.73 | PSMB8 (0.55) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL7349965 | 0.73 | DAO (0.66) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL17874917 | 0.73 | PARP1 (0.52) | MEN1KMT2APARP1KDM4EGRIN2D | |
| SCHEMBL29064867 | 0.72 | GRIA1 (0.54) | PARP1KDM4EGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647137-A4 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF. | UNIV CALIFORNIA WEBER ECKARD (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |