Methane

Methane

SCHEMBL8559022

C.Cc1cc2c(c3c1NC(=O)C3(C)C)OC1COS(=O)(=O)CCC21

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.30
PDK4 Q16654 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8555820 0.64 PDK2 (0.32) PDK2PDK4
SCHEMBL8556913 0.64
SCHEMBL8556907 0.64
SCHEMBL8557345 0.64
SCHEMBL8554838 0.64
SCHEMBL8556240 0.64
SCHEMBL8561081 0.63 PDK2 (0.33) PDK2PDK4
SCHEMBL8560157 0.63
SCHEMBL8555807 0.63
Hydrochloric Acid SCHEMBL8554220 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0653426-B1 Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same KOWA CO (JP) 1998-07-22 EP disclosed
EP-0653426-A1 Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same KOWA COMPANY, LTD. (JP) 1995-05-17 EP disclosed