Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563389 | 0.88 | MEN1 (0.45) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL8046578 | 0.86 | MEN1 (0.49) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL9842376 | 0.85 | APP (0.70) | APPCYP3A4CYP2C9CYP2C19HSD11B1 | |
| SCHEMBL7511127 | 0.85 | MEN1 (0.48) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL7507869 | 0.84 | MEN1 (0.47) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL17761265 | 0.83 | CYP3A4 (0.48) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL7507981 | 0.81 | MEN1 (0.41) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL8025330 | 0.81 | APP (0.40) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL8860551 | 0.81 | APP (0.40) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL301150 | 0.80 | APP (0.61) | APPCYP3A4CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |