Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2262554 | 0.73 | — | — | |
| SCHEMBL277137 | 0.71 | — | — | |
| SCHEMBL275706 | 0.71 | — | — | |
| SCHEMBL28814234 | 0.69 | TSHR (0.32) | TSHR | |
| SCHEMBL5028966 | 0.67 | — | — | |
| SCHEMBL10429784 | 0.65 | TSHR (0.31) | TSHR | |
| SCHEMBL19287559 | 0.64 | TSHR (0.35) | TSHR | |
| SCHEMBL22023874 | 0.62 | — | — | |
| SCHEMBL22928152 | 0.62 | — | — | |
| SCHEMBL4620857 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |