Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.69 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.63 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ARNT | P27540 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559386 | 0.91 | AKR1B1 (0.77) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2646781 | 0.86 | AKR1B1 (0.70) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10529983 | 0.85 | MAPK1 (0.76) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL13811262 | 0.85 | MAPK1 (0.75) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11468688 | 0.85 | AKR1B1 (0.72) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2641949 | 0.85 | AKR1B1 (0.69) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1668253 | 0.85 | AKR1B1 (0.69) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11392520 | 0.82 | MAPK1 (0.84) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2493312 | 0.81 | AKR1B1 (0.65) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11515701 | 0.81 | MAPT (0.72) | MAPK1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0616807-B1 | Benzimidazole useful in the treatment of central nervous system disorders | NEUROSEARCH AS (DK) | 1998-07-08 | — | — | EP | disclosed |
| US-4179436-A | DYEING POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| US-4163013-A | Diphenylamine-azo-hydrocarbylsulfonylphenyl dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-31 | — | — | US | disclosed |