Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 15/20 | 0.71 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.71 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563344 | 0.91 | AVPR2 (0.81) | AVPR2AVPR1A | |
| SCHEMBL8557043 | 0.88 | AVPR2 (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL7336291 | 0.86 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8562554 | 0.86 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8563435 | 0.84 | AVPR2 (0.74) | AVPR2AVPR1AOXTR | |
| SCHEMBL8562180 | 0.82 | AVPR2 (0.72) | AVPR2AVPR1A | |
| SCHEMBL8558027 | 0.82 | AVPR2 (0.69) | AVPR2AVPR1A | |
| SCHEMBL8558085 | 0.82 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL7333030 | 0.82 | AVPR2 (0.74) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558900 | 0.80 | AVPR2 (0.65) | AVPR2AVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |