Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8565607 | 0.99 | CSF1R (0.48) | CSF1RPDE4B | |
| SCHEMBL9544473 | 0.92 | PDE4B (0.50) | PDE4B | |
| SCHEMBL8564146 | 0.90 | CSF1R (0.50) | CSF1RPDE4B | |
| SCHEMBL8563378 | 0.89 | PDE4B (0.59) | CSF1RPDE4B | |
| SCHEMBL8565303 | 0.89 | CSF1R (0.62) | CSF1RPDE4B | |
| Hydrochloric Acid SCHEMBL811230 | 0.89 | PDE4B (0.58) | CSF1RPDE4B | |
| SCHEMBL8569260 | 0.85 | PDE4B (0.56) | CSF1RPDE4B | |
| SCHEMBL8558688 | 0.84 | PDE4B (0.60) | CSF1RPDE4B | |
| Hydrochloric Acid SCHEMBL8560512 | 0.84 | PDE4B (0.55) | PDE4B | |
| SCHEMBL8561356 | 0.84 | PDE4B (0.44) | CSF1RPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | disclosed |
| US-5464781-A | TREATING RHEUMATIC DISEASES | THE BOOTS COMPANY PLC (GB) | 1995-11-07 | — | — | US | disclosed |
| EP-0618916-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013097-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |