Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559537 | 1.00 | HCRTR2 (0.38) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8557886 | 0.90 | HCRTR2 (0.38) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8554401 | 0.90 | HCRTR2 (0.38) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8554399 | 0.90 | HCRTR2 (0.38) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8557714 | 0.90 | HCRTR2 (0.37) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8556600 | 0.90 | HCRTR2 (0.37) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8556603 | 0.90 | HCRTR2 (0.37) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| Hydrochloric Acid SCHEMBL8557259 | 0.76 | — | — | |
| SCHEMBL8556610 | 0.71 | HCRTR2 (0.33) | HCRTR2BRD4CREBBPL3MBTL1SERPINE1 | |
| SCHEMBL8554438 | 0.70 | NPSR1 (0.33) | HCRTR2KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |