Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532132 | 0.84 | GUCY1B2 (0.46) | — | |
| SCHEMBL9747203 | 0.80 | PSEN1 (0.43) | — | |
| SCHEMBL12797510 | 0.79 | HRH3 (0.48) | PTGER1 | |
| SCHEMBL8565013 | 0.78 | GUCY1B2 (0.47) | — | |
| SCHEMBL8567556 | 0.78 | PSEN1 (0.48) | — | |
| SCHEMBL12797495 | 0.77 | NPC1 (0.59) | PTGER1 | |
| SCHEMBL2191140 | 0.77 | MEN1 (0.51) | — | |
| SCHEMBL9749030 | 0.77 | PSEN1 (0.53) | — | |
| SCHEMBL9748883 | 0.77 | PTGER1 (0.44) | PTGER1 | |
| SCHEMBL12848887 | 0.77 | PPARG (0.48) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |