Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148218 | 0.86 | FGFR1 (0.49) | KDRFGFR1MTORADKNISCH | |
| SCHEMBL8462814 | 0.85 | FGFR1 (0.41) | FGFR1MTORADKNISCHALDH1A1 | |
| SCHEMBL12135624 | 0.80 | KDR (0.76) | KDRFGFR1HTTALDH1A1 | |
| SCHEMBL24900303 | 0.77 | KDR (0.60) | KDRFGFR1HTTALDH1A1 | |
| SCHEMBL30083763 | 0.77 | KDR (0.60) | KDRFGFR1HTTALDH1A1 | |
| SCHEMBL4015486 | 0.76 | HTT (0.71) | KDRFGFR1HTT | |
| SCHEMBL3644191 | 0.76 | NISCH (0.74) | MTORADKNISCHALDH1A1 | |
| SCHEMBL2643550 | 0.76 | FGFR1 (0.78) | KDRFGFR1HTTALDH1A1 | |
| SCHEMBL16147335 | 0.76 | KDM4E (0.47) | FGFR1HTTALDH1A1 | |
| SCHEMBL7677283 | 0.75 | KDR (0.68) | KDRFGFR1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0616807-B1 | Benzimidazole useful in the treatment of central nervous system disorders | NEUROSEARCH AS (DK) | 1998-07-08 | — | — | EP | claimed |