Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.63 |
| ▸ | PPARA | Q07869 | 12/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.49 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559845 | 1.00 | PPARG (0.63) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL8564512 | 1.00 | PPARG (0.63) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL8559217 | 0.90 | PPARG (0.53) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8559220 | 0.90 | PPARG (0.53) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8561360 | 0.88 | PPARG (0.49) | PPARGPPARASLC1A5SLC1A3SLC1A2 | |
| SCHEMBL8561366 | 0.88 | PPARG (0.49) | PPARGPPARASLC1A5SLC1A3SLC1A2 | |
| SCHEMBL8561508 | 0.88 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL8561497 | 0.88 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL8595655 | 0.85 | PPARG (0.68) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8562657 | 0.85 | PPARG (0.68) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |