Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.65 |
| ▸ | OXTR | P30559 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561006 | 0.93 | AVPR2 (0.75) | AVPR2AVPR1AOXTR | |
| SCHEMBL8556275 | 0.92 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333830 | 0.88 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL7351861 | 0.88 | AVPR2 (0.81) | AVPR2AVPR1AOXTR | |
| SCHEMBL7345440 | 0.87 | AVPR1A (0.86) | AVPR2AVPR1AOXTR | |
| SCHEMBL7344384 | 0.86 | AVPR1A (0.63) | AVPR2AVPR1AOXTR | |
| SCHEMBL7348365 | 0.86 | AVPR1A (0.85) | AVPR2AVPR1AOXTR | |
| SCHEMBL8563255 | 0.85 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| Hydrochloric Acid SCHEMBL7354212 | 0.85 | AVPR1A (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558030 | 0.84 | AVPR2 (0.61) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |