Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU2 | Q9Y3R4 | 7/20 | 0.69 |
| ▸ | NEU4 | Q8WWR8 | 6/20 | 0.69 |
| ▸ | NEU3 | Q9UQ49 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | NEU1 | Q99519 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563620 | 0.92 | NEU2 (0.69) | NEU2NEU4NEU3LMNANEU1 | |
| SCHEMBL8563443 | 0.92 | NEU2 (0.69) | NEU2NEU4NEU3LMNANEU1 | |
| SCHEMBL2631658 | 0.89 | NEU2 (0.73) | NEU2NEU4NEU3LMNANEU1 | |
| SCHEMBL28036256 | 0.89 | NEU2 (0.73) | NEU2NEU4NEU3LMNANEU1 | |
| SCHEMBL6018157 | 0.89 | NEU2 (0.78) | NEU2NEU4NEU3LMNANEU1 | |
| Zanamivir SCHEMBL13980833 | 0.88 | NEU2 (0.72) | NEU2NEU4NEU3LMNANEU1 | |
| Zanamivir SCHEMBL3497032 | 0.88 | NEU2 (0.72) | NEU2NEU4NEU3LMNANEU1 | |
| Zanamivir SCHEMBL15448958 | 0.88 | NEU2 (0.72) | NEU2NEU4NEU3LMNANEU1 | |
| Zanamivir SCHEMBL13169991 | 0.88 | NEU2 (0.72) | NEU2NEU4NEU3LMNANEU1 | |
| Zanamivir SCHEMBL12367840 | 0.88 | NEU2 (0.72) | NEU2NEU4NEU3LMNANEU1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539204-B1 | Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid | BIOTA SCIENT MANAGEMENT (AU) | 1998-01-07 | — | — | EP | claimed |
| US-5639786-A | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid | BIOTA SCIENTIFIC MANAGEMENT, PTY., LTD. (AU) | 1997-06-17 | — | — | US | claimed |
| EP-0539204-A1 | Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1993-04-28 | — | — | EP | claimed |
| US-5639786-A | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid | BIOTA SCIENTIFIC MANAGEMENT, PTY., LTD. (AU) | 1997-06-17 | — | — | US | disclosed |
| EP-0539204-A1 | Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1993-04-28 | — | — | EP | disclosed |