Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8560091 | 0.96 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8567598 | 0.90 | HTR1D (0.73) | HTR1DHTR1B | |
| Oxalic Acid SCHEMBL8559245 | 0.87 | HTR1D (0.69) | HTR1DHTR1B | |
| Dimethylamine SCHEMBL8784885 | 0.85 | HTR1D (0.72) | HTR1DHTR1B | |
| SCHEMBL8564279 | 0.83 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL8564091 | 0.83 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL7474143 | 0.83 | HTR1D (1.00) | HTR1DHTR1B | |
| Oxalic Acid SCHEMBL8786566 | 0.82 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL7479099 | 0.80 | HTR1D (0.80) | HTR1DHTR1B | |
| SCHEMBL7479104 | 0.80 | HTR1D (0.80) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807109-A1 | SUBSTITUTED 1,4-PIPERAZINE-HETEROARYL DERIVATIVES AS 5-HT 1D? RECEPTOR AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1997-11-19 | — | — | EP | claimed |
| WO-1996023785-A1 | SUBSTITUTED 1,4-PIPERAZINE-HETEROARYL DERIVATIVES AS 5-HT1D RECEPTOR AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-08-08 | — | — | WO | claimed |
| US-5849746-A | Substituted 1,4-piperazine-heteroaryl derivatives as 5-HT1D receptor agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-12-15 | — | — | US | disclosed |
| EP-0807109-A1 | SUBSTITUTED 1,4-PIPERAZINE-HETEROARYL DERIVATIVES AS 5-HT 1D? RECEPTOR AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023785-A1 | SUBSTITUTED 1,4-PIPERAZINE-HETEROARYL DERIVATIVES AS 5-HT1D RECEPTOR AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-08-08 | — | — | WO | disclosed |