Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561712 | 0.94 | HTR2C (0.46) | HTR2CSLC6A2SLC6A4ESR2PSEN1 | |
| SCHEMBL8562055 | 0.92 | HTR2C (0.44) | HTR2CSLC6A2SLC6A4ESR2PSEN1 | |
| SCHEMBL8565160 | 0.90 | SLC6A2 (0.43) | HTR2CSLC6A2SLC6A4ESR2PSEN1 | |
| SCHEMBL8044836 | 0.86 | AKR1C3 (0.42) | HTR2CSLC6A2SLC6A4CETPP2RY14 | |
| SCHEMBL8048330 | 0.85 | SLC6A2 (0.38) | HTR2CDGAT1SOAT1SLC6A2SLC6A4 | |
| SCHEMBL8034581 | 0.85 | ESR2 (0.34) | DGAT1SOAT1ESR2CETPALDH1A1 | |
| SCHEMBL11286081 | 0.85 | HTR2C (0.47) | HTR2CDGAT1SOAT1ESR2ALDH1A1 | |
| SCHEMBL8567945 | 0.84 | MAOB (0.46) | SLC6A2SLC6A4MCHR1ALDH1A1TMEM97 | |
| SCHEMBL10453440 | 0.83 | HTR2C (0.46) | HTR2CDGAT1SOAT1ESR2ALDH1A1 | |
| SCHEMBL11285346 | 0.83 | HTR2C (0.46) | HTR2CDGAT1SOAT1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |