Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561460 | 1.00 | EPHX2 (0.52) | EPHX2MTNR1AMTNR1BMAPK1HDAC8 | |
| SCHEMBL8561461 | 1.00 | EPHX2 (0.52) | EPHX2MTNR1AMTNR1BMAPK1HDAC8 | |
| SCHEMBL11635763 | 0.84 | EPHX2 (0.41) | EPHX2MTNR1AMTNR1BMAPK1CA1 | |
| SCHEMBL1600966 | 0.78 | CA1 (0.48) | MTNR1AMTNR1BMAPTCA1CA2 | |
| SCHEMBL4798460 | 0.77 | EPHX2 (0.56) | EPHX2MTNR1AMTNR1BMAPK1BRD4 | |
| SCHEMBL4798922 | 0.77 | EPHX2 (0.56) | EPHX2MTNR1AMTNR1BMAPK1BRD4 | |
| SCHEMBL429344 | 0.75 | EPHX2 (0.66) | EPHX2MTNR1AMTNR1BMAPK1HDAC8 | |
| SCHEMBL8568435 | 0.74 | EPHX2 (0.68) | EPHX2MTNR1AMTNR1BMAPK1HDAC8 | |
| SCHEMBL4830429 | 0.74 | EPHX2 (0.68) | EPHX2MTNR1AMTNR1BMAPK1HDAC8 | |
| SCHEMBL8568429 | 0.74 | EPHX2 (0.68) | EPHX2MTNR1AMTNR1BMAPK1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |