Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561899 | 1.00 | PDE10A (0.49) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9000299 | 0.84 | PDE10A (0.54) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1092487 | 0.83 | PDE10A (0.49) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL13351976 | 0.83 | PDE10A (0.49) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1092129 | 0.83 | PDE10A (0.49) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1092131 | 0.83 | PDE10A (0.49) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29953235 | 0.80 | PDE10A (0.53) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL305885 | 0.80 | PDE10A (0.53) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1736681 | 0.80 | TAAR1 (0.57) | PDE10APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1736679 | 0.80 | TAAR1 (0.57) | PDE10APOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |