Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661196 | 0.91 | MAPT (0.35) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL20835285 | 0.77 | MAPT (0.32) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL8472078 | 0.76 | — | — | |
| SCHEMBL7704607 | 0.76 | MAPT (0.35) | MAPT | |
| SCHEMBL8568039 | 0.75 | KCNH2 (0.43) | — | |
| SCHEMBL135037 | 0.72 | CHRM1 (0.54) | KDM4ESMN1; SMN2 | |
| SCHEMBL23528233 | 0.71 | MAPT (0.46) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL132520 | 0.71 | MAPT (0.46) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL9785641 | 0.71 | MAPT (0.46) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL2157617 | 0.71 | MAPT (0.46) | MAPTKDM4EALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808160-A | Preparation of hydroxy-alkyl-substituted aminoalkynes with heterogenous catalysis | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |