Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562385 | 0.88 | USP2 (0.58) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL21307088 | 0.85 | MAPT (0.65) | MAPTALDH1A1HSD17B10ATMTSHR | |
| SCHEMBL223446 | 0.84 | HSD17B10 (0.55) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL20602048 | 0.83 | MAPT (0.53) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL8888393 | 0.82 | MAPT (0.51) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL1345863 | 0.82 | MAPT (0.51) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL11949139 | 0.82 | CYP1A2 (0.57) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL8203218 | 0.81 | MAPT (0.48) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| Hydrochloric Acid SCHEMBL25376018 | 0.81 | RAD52 (0.52) | MAPTALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL21879061 | 0.81 | EP300 (0.56) | MAPTALDH1A1HSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |