Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | MDH1 | P40925 | 3/20 | 0.39 |
| ▸ | MDH2 | P40926 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563110 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4PPARGPPARASHBG | |
| SCHEMBL31151825 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4PPARGPPARASHBG | |
| Hydrochloric Acid SCHEMBL10387366 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP3A4PPARGPPARASHBG | |
| SCHEMBL8559406 | 0.81 | PPARG (0.62) | PPARGPPARAKIF11 | |
| SCHEMBL8559402 | 0.81 | PPARG (0.62) | PPARGPPARAKIF11 | |
| SCHEMBL8558724 | 0.79 | PPARG (0.55) | SMN1; SMN2PPARGPPARAKIF11 | |
| SCHEMBL8558721 | 0.79 | PPARG (0.55) | SMN1; SMN2PPARGPPARAKIF11 | |
| SCHEMBL8559317 | 0.79 | PPARG (0.55) | SMN1; SMN2PPARGPPARAKIF11 | |
| SCHEMBL8560351 | 0.79 | PPARG (0.59) | SMN1; SMN2PPARGPPARAKIF11 | |
| SCHEMBL8559217 | 0.77 | PPARG (0.53) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |