⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707454 | 0.78 | — | — | |
| SCHEMBL776631 | 0.69 | — | — | |
| Chloroform SCHEMBL28203855 | 0.69 | — | — | |
| SCHEMBL777285 | 0.67 | — | — | |
| SCHEMBL15172357 | 0.65 | — | — | |
| SCHEMBL177012 | 0.65 | — | — | |
| SCHEMBL12207182 | 0.65 | — | — | |
| SCHEMBL4589747 | 0.65 | — | — | |
| SCHEMBL1935002 | 0.65 | — | — | |
| SCHEMBL5196515 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433951-A2 | A process for the preparation of drospirenone | Industriale Chimica S.R.L. (IT) | 2012-03-28 | — | — | EP | claimed |
| EP-1571153-B1 | A process for the preparation of drospirenone | IND CHIMICA SRL (IT) | 2010-11-03 | — | — | EP | claimed |
| US-7585971-B2 | Process for the preparation of drospirenone | INDUSTRIALE CHIMICA S.R.L. (IT) | 2009-09-08 | — | — | US | claimed |
| EP-1571153-A2 | A process for the preparation of drospirenone | INDUSTRIALE CHIMICA S.r.l. (IT) | 2005-09-07 | — | — | EP | claimed |
| US-20050192450-A1 | Process for the preparation of drospirenone | INDUSTRIALE CHIMICA S.R.L. | 2005-09-01 | — | — | US | claimed |
| EP-2433951-A2 | A process for the preparation of drospirenone | Industriale Chimica S.R.L. (IT) | 2012-03-28 | — | — | EP | disclosed |
| EP-1571153-B1 | A process for the preparation of drospirenone | IND CHIMICA SRL (IT) | 2010-11-03 | — | — | EP | disclosed |
| US-7585971-B2 | Process for the preparation of drospirenone | INDUSTRIALE CHIMICA S.R.L. (IT) | 2009-09-08 | — | — | US | disclosed |
| EP-1571153-A2 | A process for the preparation of drospirenone | INDUSTRIALE CHIMICA S.r.l. (IT) | 2005-09-07 | — | — | EP | disclosed |
| US-20050192450-A1 | Process for the preparation of drospirenone | INDUSTRIALE CHIMICA S.R.L. | 2005-09-01 | — | — | US | disclosed |
| US-4113680-A | Method for preparing 17 α-ester-21-halo pregnanes | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |