SCHEMBL8564158

SCHEMBL8564158

O=Cc1cc(F)c(O)c(F)c1O

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 19/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31312489 1.00 ERN1 (0.65) ERN1
SCHEMBL6332603 0.86 ERN1 (0.59) ERN1
SCHEMBL3693663 0.86 ERN1 (0.59) ERN1
SCHEMBL12038484 0.80 ERN1 (0.59) ERN1
SCHEMBL20722554 0.80 ERN1 (0.54) ERN1
SCHEMBL24133309 0.80 ERN1 (0.53) ERN1
SCHEMBL29740541 0.79 ERN1 (1.00) ERN1
SCHEMBL1405241 0.79 ERN1 (1.00) ERN1
SCHEMBL3664243 0.77 ERN1 (0.75) ERN1
SCHEMBL29956081 0.77 ERN1 (0.75) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698520-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF Gandeeva Therapeutics, Inc. (US) 2026-02-25 EP disclosed
EP-4676919-A1 MONOFLUORINATED COUMARIN FLUOROPHORES AND USES THEREOF Ohio State Innovation Foundation (US) 2026-01-14 EP disclosed
EP-4496854-A1 VIOLET EXCITABLE TANDEM DYES, AND METHODS FOR MAKING AND USING THE SAME Becton, Dickinson and Company (US) 2025-01-29 EP disclosed
WO-2024220708-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF GANDEEVA THERAPEUTICS, INC. (US) 2024-10-24 WO disclosed
WO-2024186721-A1 MONOFLUORINATED COUMARIN FLUOROPHORES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-09-12 WO disclosed
WO-2023183152-A1 VIOLET EXCITABLE TANDEM DYES, AND METHODS FOR MAKING AND USING THE SAME BECTON, DICKINSON AND COMPANY (US) 2023-09-28 WO disclosed
WO-2023183152-A1 VIOLET EXCITABLE TANDEM DYES, AND METHODS FOR MAKING AND USING THE SAME BECTON, DICKINSON AND COMPANY (US) 2023-09-28 WO disclosed
US-20230295440-A1 VIOLET EXCITABLE TANDEM DYES, AND METHODS FOR MAKING AND USING THE SAME BECTON, DICKINSON AND COMPANY 2023-09-21 US disclosed
US-20230295440-A1 VIOLET EXCITABLE TANDEM DYES, AND METHODS FOR MAKING AND USING THE SAME BECTON, DICKINSON AND COMPANY 2023-09-21 US disclosed
US-20230295440-A1 VIOLET EXCITABLE TANDEM DYES, AND METHODS FOR MAKING AND USING THE SAME BECTON, DICKINSON AND COMPANY 2023-09-21 US disclosed
US-5830912-A Derivatives of 6,8-difluoro-7-hydroxycoumarin MOLECULAR PROBES, INC. (US) 1998-11-03 US disclosed
US-5773236-A FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS MOLECULE PROBES, INC. (US) 1998-06-30 US disclosed