Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25482213 | 0.79 | CYP2A6 (0.53) | CYP2A6CNR2PLAUPLGF12 | |
| SCHEMBL6449048 | 0.79 | PLAU (0.53) | CYP2A6CNR2KDM4EPLAUPLG | |
| SCHEMBL6603107 | 0.79 | PLAU (0.53) | CYP2A6CNR2KDM4EPLAUPLG | |
| SCHEMBL8250524 | 0.78 | CYP2A6 (0.52) | CYP2A6CNR2PLAUPLGF12 | |
| SCHEMBL349832 | 0.78 | CNR2 (0.56) | CYP2A6CNR2PLAUPLGF12 | |
| SCHEMBL18576588 | 0.78 | CYP2A6 (0.52) | CYP2A6CNR2PLAUPLGF12 | |
| SCHEMBL9024733 | 0.77 | CNR2 (0.46) | CASP3GFERSENP8SENP7SENP6 | |
| SCHEMBL25264654 | 0.76 | TSHR (0.40) | CYP2A6CNR2PLAUPLGF12 | |
| SCHEMBL30166161 | 0.76 | TSHR (0.40) | CYP2A6CNR2PLAUPLGF12 | |
| SCHEMBL23898793 | 0.76 | TSHR (0.40) | CYP2A6CNR2PLAUPLGF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664795-B1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LTD (GB) | 1998-07-01 | — | — | EP | disclosed |
| US-5723473-A | Propenoic acid derivatives useful as fungicides | ZENECA LIMITED (GB) | 1998-03-03 | — | — | US | disclosed |
| EP-0664795-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008968-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |