Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.64 |
| ▸ | PPARA | Q07869 | 11/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559718 | 1.00 | PPARG (0.64) | PPARGPPARAGRIK1GRIK2GRIK3 | |
| SCHEMBL8560729 | 1.00 | PPARG (0.64) | PPARGPPARAGRIK1GRIK2GRIK3 | |
| SCHEMBL8559217 | 0.85 | PPARG (0.53) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8559220 | 0.85 | PPARG (0.53) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8557408 | 0.85 | PPARG (0.47) | PPARGPPARAGRIK1GRIK2GRIK3 | |
| SCHEMBL8560324 | 0.85 | PPARG (0.47) | PPARGPPARAGRIK1GRIK2GRIK3 | |
| SCHEMBL8557407 | 0.85 | PPARG (0.47) | PPARGPPARAGRIK1GRIK2GRIK3 | |
| SCHEMBL8564512 | 0.83 | PPARG (0.63) | PPARGPPARAGRIK1GRIK2SLC1A3 | |
| SCHEMBL8561497 | 0.83 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL8561508 | 0.83 | PPARG (0.63) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |