Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 12/20 | 0.34 |
| ▸ | DRD3 | P35462 | 7/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564964 | 1.00 | F2 (0.35) | F2F10DRD2DRD3KHK | |
| Hydrochloric Acid SCHEMBL8561299 | 0.92 | F2 (0.35) | F2F10DRD2DRD3KHK | |
| SCHEMBL8562703 | 0.92 | F2 (0.35) | F2F10DRD2DRD3KHK | |
| SCHEMBL8562707 | 0.92 | F2 (0.35) | F2F10DRD2DRD3KHK | |
| SCHEMBL7468689 | 0.91 | HRH3 (0.40) | F2F10KHKUSP30 | |
| Hydrochloric Acid SCHEMBL8561453 | 0.91 | F2 (0.35) | F2F10DRD2DRD3KHK | |
| SCHEMBL7472292 | 0.90 | F2 (0.34) | F2F10DRD2DRD3KHK | |
| SCHEMBL7474107 | 0.90 | PARP1 (0.38) | F2F10DRD2DRD3 | |
| SCHEMBL7474111 | 0.90 | PARP1 (0.38) | F2F10DRD2DRD3 | |
| SCHEMBL7472286 | 0.90 | F2 (0.34) | F2F10DRD2DRD3KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612741-B1 | Cyclic derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-06-10 | — | — | EP | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |