Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573018 | 0.87 | KCNH2 (0.42) | KCNH2SCN5A | |
| SCHEMBL8565903 | 0.87 | SCN5A (0.44) | KCNH2SCN5AKDM4EALDH1A1POLB | |
| SCHEMBL8570477 | 0.86 | SCN5A (0.45) | KCNH2SCN5AKDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8893794 | 0.86 | KCNH2 (0.42) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL8573819 | 0.86 | SCN5A (0.44) | KCNH2SCN5AKDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7496978 | 0.86 | SCN5A (0.45) | KCNH2SCN5AKDM4EALDH1A1POLB | |
| SCHEMBL7927938 | 0.85 | SCN5A (0.44) | KCNH2SCN5AALDH1A1POLBCHRM2 | |
| SCHEMBL8893288 | 0.85 | SCN5A (0.42) | KCNH2SCN5AKDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9055075 | 0.85 | SCN5A (0.43) | KCNH2SCN5AKDM4EALDH1A1 | |
| SCHEMBL8563910 | 0.84 | SCN5A (0.44) | KCNH2SCN5AALDH1A1POLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |