SCHEMBL8565570

SCHEMBL8565570

OCCCOC1(OCCCO)C=CC(c2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SLC18A3 Q16572 2/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
TP53 P04637 1/20 0.30
MDM2 Q00987 1/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9489197 0.77 PARP1 (0.33) PARP1MEN1KMT2AALDH1A1
SCHEMBL9490170 0.77 PARP1 (0.33) PARP1MEN1KMT2AALDH1A1
SCHEMBL7199616 0.76 PPARG (0.32) ALDH1A1
SCHEMBL6694141 0.76
SCHEMBL5472352 0.74 CYP1A2 (0.42) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL8393068 0.70 TDP1 (0.45) MEN1KMT2AALDH1A1TP53
SCHEMBL10449056 0.70 PPARG (0.42) MEN1KMT2AALDH1A1RECQLLMNA
SCHEMBL21224652 0.70 PPARG (0.42) MEN1KMT2AALDH1A1RECQLLMNA
SCHEMBL3684570 0.70 KDM1A (0.40) SLC18A3ALDH1A1LMNATP53KDM1A
SCHEMBL5185255 0.70 POLB (0.34) POLBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773178-A Process for producing a patterned anisotropic polymeric film JAPAN SYNTHETIC RUBBER CO, LTD. (JP) 1998-06-30 US disclosed