Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327645 | 0.91 | KMT2A (0.51) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL8327213 | 0.88 | DPP4 (0.49) | DPP4KMT2AMEN1MAPTKDM4E | |
| SCHEMBL8566663 | 0.84 | KMT2A (0.51) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL2921747 | 0.81 | DPP4 (0.58) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL30449564 | 0.81 | DPP4 (0.58) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL8326372 | 0.80 | TSHR (0.40) | DPP4KMT2AMEN1GAAKDM4E | |
| SCHEMBL30629571 | 0.80 | MAPT (0.62) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL23144946 | 0.79 | KMT2A (0.57) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL29843236 | 0.79 | KMT2A (0.57) | DPP4KMT2AMEN1MAPTGAA | |
| SCHEMBL8326185 | 0.79 | SLC2A1 (0.40) | DPP4KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | disclosed |