Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564116 | 1.00 | SCN5A (0.40) | SCN5AKCNH2TOP1OPRL1BTK | |
| SCHEMBL8570796 | 1.00 | SCN5A (0.40) | SCN5AKCNH2TOP1OPRL1BTK | |
| Hydrochloric Acid SCHEMBL8573942 | 0.99 | SCN5A (0.39) | SCN5AKCNH2TOP1OPRL1BTK | |
| Hydrochloric Acid SCHEMBL8570706 | 0.99 | SCN5A (0.39) | SCN5AKCNH2TOP1OPRL1BTK | |
| Hydrochloric Acid SCHEMBL8570616 | 0.99 | SCN5A (0.39) | SCN5AKCNH2TOP1OPRL1BTK | |
| SCHEMBL8566822 | 0.89 | SCN5A (0.39) | SCN5AKCNH2TOP1OPRL1BTK | |
| SCHEMBL8569098 | 0.88 | KCNH2 (0.42) | SCN5AKCNH2TOP1BTKDYRK3 | |
| SCHEMBL8569090 | 0.88 | KCNH2 (0.42) | SCN5AKCNH2TOP1BTKDYRK3 | |
| Hydrochloric Acid SCHEMBL8577566 | 0.88 | SCN5A (0.39) | SCN5AKCNH2TOP1OPRL1BTK | |
| SCHEMBL8574368 | 0.88 | SCN5A (0.40) | SCN5AKCNH2TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | claimed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |