SCHEMBL8566560

SCHEMBL8566560

CCc1cc2c(cc1[N+](=O)[O-])-c1c(cc([N+](=O)[O-])cc1[N+](=O)[O-])C2=Nc1ccccc1C(C)C

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.45
MAPT P10636 4/20 0.36
TDP1 Q9NUW8 4/20 0.36
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPRT1 P00492 1/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
CNR2 P34972 2/20 0.30
POLB P06746 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765421 0.86 HSP90AA1 (0.60) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8570567 0.85 HSP90AA1 (0.48) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8575241 0.85 HSP90AA1 (0.46) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8571939 0.83 HSP90AA1 (0.45) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8573732 0.81 HSP90AA1 (0.53) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8573092 0.80 HSP90AA1 (0.52) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8570399 0.79 HSP90AA1 (0.53) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8572960 0.78 HSP90AA1 (0.45) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8573077 0.78 HSP90AA1 (0.52) HSP90AA1MAPTTDP1MAPK1L3MBTL1
SCHEMBL8572317 0.77 HSP90AA1 (0.42) HSP90AA1L3MBTL1HPRT1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8295659-A None JP disclosed
US-RE42189-E1 Single-layer type electrophotosensitive material and image forming apparatus using the same KYOCERA MITA CORPORATION (JP) 2011-03-01 US disclosed
US-RE42189-E1 Single-layer type electrophotosensitive material and image forming apparatus using the same KYOCERA MITA CORPORATION (JP) 2011-03-01 US disclosed
US-RE39516-E1 Single-layer type electrophotosensitive material and image forming apparatus using the same KYOCERA MITA CORPORATION (JP) 2007-03-13 US disclosed
US-RE39516-E1 Single-layer type electrophotosensitive material and image forming apparatus using the same KYOCERA MITA CORPORATION (JP) 2007-03-13 US disclosed
US-5705694-A Trinitrofluoroenonimine derivative and electrophotosensitive material using the same MITA INDUSTRIAL CO., LTD. (JP) 1998-01-06 US disclosed
JP-H08295659-A TRINITROFLUORENONEIMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC SENSITIZER USING THE SAME MITA IND CO LTD 1996-11-12 JP disclosed
EP-0716078-A1 2-Ethyl-3,5,7-trinitrofluorenonimine derivative and use as charge transport MITA INDUSTRIAL CO. LTD. (JP) 1996-06-12 EP disclosed