Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573074 | 0.90 | HTT (0.38) | HTTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8571022 | 0.90 | HTT (0.38) | HTTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8568691 | 0.83 | PDE5A (0.32) | HTTMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8568393 | 0.81 | CNR2 (0.40) | HTTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8569405 | 0.78 | CNR2 (0.39) | HTTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8568175 | 0.73 | SMPD1 (0.34) | HTTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8571759 | 0.72 | CYP1A2 (0.41) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL7524338 | 0.71 | RARB (0.42) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7525022 | 0.71 | RARB (0.42) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7514377 | 0.71 | RARB (0.42) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |