Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815243 | 0.78 | PRMT5 (0.47) | PRMT5PSMB8CYP1A2CYP2A6PARP1 | |
| SCHEMBL17186937 | 0.74 | PRMT5 (0.40) | PRMT5PSMB8 | |
| SCHEMBL5000469 | 0.72 | PRMT5 (0.41) | PRMT5PSMB8 | |
| SCHEMBL10832749 | 0.68 | GRM2 (0.36) | CYP1A2CYP2A6PARP1 | |
| SCHEMBL3282387 | 0.64 | KDM4E (0.49) | PRMT5PSMB8 | |
| SCHEMBL14717084 | 0.62 | MEN1 (0.35) | — | |
| SCHEMBL1359399 | 0.61 | PSMB8 (0.41) | PRMT5PSMB8CYP1A2CYP2A6GUSB | |
| SCHEMBL2274904 | 0.60 | PSMB8 (0.38) | PRMT5PSMB8PARP1 | |
| SCHEMBL21187468 | 0.60 | DPP4 (0.51) | PRMT5PSMB8 | |
| SCHEMBL10775894 | 0.60 | DPP4 (0.51) | PRMT5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |