Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796053 | 0.91 | HSP90AA1 (0.46) | HSP90AA1NOS3NOS1NOS2TDP1 | |
| Hydrochloric Acid SCHEMBL10469678 | 0.90 | HSP90AA1 (0.44) | HSP90AA1NOS3NOS1NOS2TDP1 | |
| Hydrochloric Acid SCHEMBL10469680 | 0.90 | HSP90AA1 (0.44) | HSP90AA1NOS3NOS1NOS2TDP1 | |
| SCHEMBL11410683 | 0.82 | MEN1 (0.45) | HSP90AA1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6583708 | 0.82 | CHRNB4 (0.49) | HSP90AA1ALDH1A1TDP1SMN1; SMN2HTT | |
| SCHEMBL6583712 | 0.82 | CHRNB4 (0.49) | HSP90AA1ALDH1A1TDP1SMN1; SMN2HTT | |
| SCHEMBL394579 | 0.81 | MEN1 (0.54) | HSP90AA1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6795622 | 0.78 | HSP90AA1 (0.44) | HSP90AA1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10469676 | 0.78 | HSP90AA1 (0.44) | HSP90AA1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11413161 | 0.78 | GAA (0.47) | HSP90AA1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750567-A | TETRAHYDRONAPHTHYL DERIVATIVES | PHONE-POULENC RORER SA. (FR) | 1998-05-12 | — | — | US | disclosed |
| US-4214093-A | PROTEOLYTIC ENZYME INHIBITORS | TORII & CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |