Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8566906 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL9094186 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL3648692 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL8567000 | 0.78 | — | — | |
| SCHEMBL11789354 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL4025141 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL537369 | 0.67 | — | — | |
| SCHEMBL4349394 | 0.67 | — | — | |
| Fluoride SCHEMBL778430 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL11415565 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840338-A | THERMAL AND CHEMICAL STABILITY | MEDLOGIC GLOBAL LIMITED (GB) | 1998-11-24 | — | — | US | disclosed |
| US-5674521-A | DRUG DELIVERY SYSTEM COMPRISING POLYMER GEL NETWORK INCLUDING BIOLOGICALLY ACTIVE SOLUTE, SALT, LOADING POLYMER; REDUCED LOSS OF ACTIVITY | UNIVERSITY OF CINCINNATI (US) | 1997-10-07 | — | — | US | disclosed |
| US-5603955-A | GEL NETWORK; PROTECTIVE POLYMER; PROTECTANT SALT | UNIVERSITY OF CINCINNATI (US) | 1997-02-18 | — | — | US | disclosed |