Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567344 | 1.00 | SMYD3 (0.63) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL8567341 | 1.00 | SMYD3 (0.63) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL25937486 | 0.91 | SMYD3 (0.53) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL13610792 | 0.84 | GAA (0.65) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL30146036 | 0.84 | GAA (0.65) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL30284116 | 0.84 | SMYD3 (0.62) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL5245111 | 0.82 | SMYD3 (0.56) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL30357987 | 0.82 | SMYD3 (0.56) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL4019694 | 0.82 | SMYD3 (0.58) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL926907 | 0.81 | SMYD3 (0.56) | SMYD3MTNR1AHTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |