Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567399 | 1.00 | NAMPT (0.40) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL16384801 | 0.82 | NAMPT (0.43) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL8567394 | 0.81 | NAMPT (0.41) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL8567303 | 0.81 | NAMPT (0.46) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL8567306 | 0.81 | NAMPT (0.46) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL16385106 | 0.81 | NAMPT (0.46) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL8567308 | 0.81 | NAMPT (0.46) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL16353469 | 0.81 | NAMPT (0.42) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL16353534 | 0.81 | NAMPT (0.42) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 | |
| SCHEMBL6410947 | 0.80 | NAMPT (0.46) | NAMPTMTNR1AMTNR1BKDM1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |