Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170554 | 0.87 | KDM4E (0.57) | IKBKBKDM4ENPC1GLAMAPT | |
| Hydrochloric Acid SCHEMBL27839230 | 0.85 | KDM4E (0.56) | IKBKBKDM4ENPC1GLAMAPT | |
| SCHEMBL13906511 | 0.83 | KDM4E (0.49) | KDM4ENPC1GLAMAPTRAB9A | |
| SCHEMBL5032068 | 0.79 | CHEK2 (0.50) | IKBKBKDM4ENPC1GLAMAPT | |
| SCHEMBL12495674 | 0.76 | IKBKB (0.68) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL20750383 | 0.76 | KDM4E (0.59) | KDM4ENPC1GLAMAPTRAB9A | |
| SCHEMBL4095895 | 0.76 | IKBKB (0.62) | IKBKBKDM4ENPC1GLAMAPT | |
| SCHEMBL29504574 | 0.75 | IKBKB (0.53) | IKBKBKDM4EALOX5ALDH1A1KMT2A | |
| SCHEMBL7063637 | 0.73 | KDM4E (0.76) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL8570029 | 0.73 | KDM4E (0.40) | KDM4ENPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |