SCHEMBL8567525

SCHEMBL8567525

CC(CO)c1ccccc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.72
GABRA1 P14867 4/20 0.60
GABRB2 P47870 3/20 0.60
POLB P06746 2/20 0.47
TRPA1 O75762 5/20 0.41
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
LMNA P02545 4/20 0.39
CA2 P00918 2/20 0.39
CYP3A4 P08684 2/20 0.39
HPGD P15428 2/20 0.39
BLM P54132 2/20 0.39
HIF1A Q16665 2/20 0.39
FAAH O00519 1/20 0.39
CA1 P00915 1/20 0.39
CYP1A2 P05177 1/20 0.39
GABRB1 P18505 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3043989 0.85 TSHR (0.50) TSHRGABRA1GABRB2POLBTRPA1
SCHEMBL20721726 0.84 TSHR (1.00) TSHRGABRA1GABRB2POLBTRPA1
SCHEMBL15485172 0.84 TSHR (1.00) TSHRGABRA1GABRB2POLBTRPA1
SCHEMBL282162 0.84 TSHR (1.00) TSHRGABRA1GABRB2POLBTRPA1
Ethylene Glycol SCHEMBL27548230 0.83 TSHR (0.88) TSHRGABRA1GABRB2POLBTRPA1
SCHEMBL14576084 0.83 TSHR (0.67) TSHRGABRA1GABRB2POLBTRPA1
Benzene SCHEMBL1836843 0.82 TSHR (0.95) TSHRGABRA1GABRB2POLBTRPA1
Hydrochloric Acid SCHEMBL7075092 0.82 TSHR (0.95) TSHRGABRA1GABRB2POLBGABRG2
Ammonia Solution, Strong SCHEMBL27764945 0.82 TSHR (0.95) TSHRGABRA1GABRB2POLBGABRG2
SCHEMBL29178964 0.82 TSHR (0.95) TSHRGABRA1GABRB2POLBGABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0429614-B1 AZOPHENYL COMPOUNDS JAMES ROBINSON LTD (GB) 1995-10-11 EP claimed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO claimed
EP-3126517-B1 MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS CEPHEID (US) 2019-10-23 EP disclosed
CN-106460058-B Modified cytosine polynucleotide oligomers and methods 赛沛 2019-07-09 CN disclosed
EP-3126372-B1 MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS CEPHEID (US) 2019-02-06 EP disclosed
CN-106459128-B Modified thymine polynucleotide oligomers and methods 赛沛 2018-05-29 CN disclosed
EP-3034528-B1 Cover net systems for encapsulation films comprising urea compounds EVONIK DEGUSSA GMBH (DE) 2017-06-21 EP disclosed
EP-3034526-B1 Cover net systems for encapsulation films EVONIK DEGUSSA GMBH (DE) 2017-06-14 EP disclosed
EP-3034529-B1 COVER NET SYSTEMS FOR ENCAPSULATION FILMS COMPRISING (METH)ACRYLAMIDE COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2017-06-14 EP disclosed
EP-3034567-B1 Cover net systems for encapsulation films comprising ethylene glycoldi(meth)acrylate compounds EVONIK DEGUSSA GMBH (DE) 2017-06-14 EP disclosed
EP-3034527-B1 Cover net systems for encapsulation films comprising bis-(alkenylamide) compounds EVONIK DEGUSSA GMBH (DE) 2017-05-31 EP disclosed
EP-3034567-A1 Cover net systems for encapsulation films comprising ethylene glycoldi(meth)acrylate compounds Evonik Degussa GmbH (DE) 2016-06-22 EP disclosed
EP-3034568-A1 Cover net systems for encapsulation films comprising triallylisocyanurate and triallylcyanurate Evonik Degussa GmbH (DE) 2016-06-22 EP disclosed
EP-3034530-A1 Cover net systems for encapsulation films comprising dienes Evonik Degussa GmbH (DE) 2016-06-22 EP disclosed
EP-3034528-A1 Cover net systems for encapsulation films comprising urea compounds Evonik Degussa GmbH (DE) 2016-06-22 EP disclosed
EP-3034531-A1 Dispersion for easy use in the production of encapsulation films Evonik Degussa GmbH (DE) 2016-06-22 EP disclosed
US-20150275278-A1 MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS CEPHEID (US) 2015-10-01 US disclosed
US-5719270-A DYES, INTERMEDIATES PARTINGTON STEVEN MICHAEL (GB) 1998-02-17 US disclosed
EP-0429614-B1 AZOPHENYL COMPOUNDS JAMES ROBINSON LTD (GB) 1995-10-11 EP disclosed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150275278-A1 MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS TYMP, POLN, POLM TSHR 3027/4885GABRA1 3977/4885GABRB2 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.