Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566015 | 0.81 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL8568460 | 0.78 | MEN1 (0.35) | MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL8565722 | 0.74 | MAPT (0.33) | MAPTHTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8564839 | 0.71 | CYP1A2 (0.37) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1840937 | 0.70 | MEN1 (0.48) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL17555611 | 0.70 | MAPT (0.44) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL28762232 | 0.70 | ADORA2A (0.42) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL8567345 | 0.69 | MAPT (0.41) | MAPTHTTLMNAKMT2AMEN1 | |
| SCHEMBL8567745 | 0.69 | MAPT (0.32) | MAPT | |
| SCHEMBL12488913 | 0.69 | MAPT (0.44) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |