Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567989 | 1.00 | HPGD (0.69) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8567992 | 1.00 | HPGD (0.69) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17432715 | 0.84 | HPGD (0.64) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15373676 | 0.83 | HPGD (0.62) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24377945 | 0.82 | HPGD (0.62) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30556479 | 0.82 | HPGD (0.62) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17432607 | 0.82 | HPGD (1.00) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8562494 | 0.82 | HPGD (0.61) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8562493 | 0.82 | HPGD (0.61) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1689603 | 0.82 | HPGD (0.61) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |