Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PBK | Q96KB5 | 9/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576057 | 0.95 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL1552957 | 0.88 | PDE4D (0.54) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| Hydrochloric Acid SCHEMBL8568573 | 0.87 | PDE4D (0.53) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL1553709 | 0.87 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL1554160 | 0.84 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL1554161 | 0.82 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| Hydrochloric Acid SCHEMBL8576071 | 0.82 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL1581071 | 0.81 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL1553706 | 0.80 | PDE4D (0.71) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8573500 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |